Trials
Search / Trial NCT06422988

Do Probiotics Reduce The Risk Of Severe Necrotising Enterocolitis (NEC) In Infants Born Before 32 Weeks Gestation?

Launched by IMPERIAL COLLEGE LONDON · May 18, 2024

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Trial Information

Current as of March 14, 2025

Enrolling by invitation

Keywords

Probiotics

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Eligible infants must have been born at less than 32 weeks gestation and be cared for in a English or Welsh unit which contributes data to the National Neonatal Research Database (this includes all NHS neonatal units in England and Wales).
  • • Infants born in the period January 1st, 2016, to December 31st, 2022 (7 years) will be included.
  • Exclusion Criteria:
  • • They have missing data for any of: gestational age at birth, birth weight, year of birth and date of death (for those that died).
  • • Their NNRD record does not include details of their first admission or begins after Day 3 of life.
  • • The absolute value of their recorded birthweight for gestational age z score exceeds 4 or is missing.
  • • They die in the first two postnatal days of life.
  • • They have a major congenital abnormality

About Imperial College London

Imperial College London is a world-renowned research institution based in the United Kingdom, recognized for its commitment to advancing medical science and improving patient care through innovative research and clinical trials. With a strong emphasis on interdisciplinary collaboration, Imperial combines expertise across various fields, including medicine, engineering, and business, to drive breakthroughs in healthcare. The institution’s robust clinical trial programs are designed to evaluate new therapies and interventions, ensuring rigorous scientific standards and ethical practices while aiming to translate research findings into tangible benefits for patients and society.

Locations

London, , United Kingdom

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0