Microfragmented Adipose Tissue Injection Compared to Hyaluronic Acid for Treatment of Temporomandibular Joint Osteoarthritis

Launched by CAIRO UNIVERSITY · May 17, 2024

Keywords

ClinConnect Summary

Rationale for conducting the research:

The rationale of this procedure is to remove inflammatory mediators, reduce friction, stimulate the production of new synovial fluid, eliminate suction-cup effect.

The purpose of this study was to evaluate the hypothesis that TMJ arthrocentesis with intraarticular injection of autologous micro fragmented adipose tissue leads to better clinical outcomes in terms of reducing pain and improving function

compared with arthrocentesis and intraarticular injection of hyaluronic acid (HA) in patients with TMJ internal derangement and osteoarthritis.

Prelim...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • \* TMJ osteoarthritis assessed by clinical examination and MRI imaging
• • Presence of TMJ-related symptoms including at least limited mouth opening and joint pain
• • Previously failed conservative treatment
• • Age superior to 14 years
• • No previous TMJ surgical procedures
• • Acquisition of informed consent;
• • Complete availability of the data acquired preoperatively and during each follow-up
• • Patients free from any systemic disease that may affect the procedure.
• Exclusion Criteria:
• • \* Previously diagnosed hematological and neurological conditions;
• • Previous malignant head and neck neoplasms;
• • Contraindication to fat harvesting.
• • Uncooperative patients.