Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

Launched by UNIVERSITY OF SAO PAULO GENERAL HOSPITAL · May 20, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how resistance training, which involves exercises using weights or resistance bands, can help patients with heart failure who are waiting for a heart transplant. The study aims to see if this type of training can improve their physical ability, quality of life, and certain heart health markers over a period of 12 weeks. Additionally, researchers will look at how different levels of frailty, which means how weak or fragile a person may be, affect the benefits they get from the training.

To be eligible for this trial, participants need to be on the heart transplant waiting list for no longer than one month and must be stable in their condition, meaning their heart function is steady. They should be aged between 65 and 74 years or 25 and 56 years, and they cannot have certain heart conditions or other health issues that would make it hard for them to complete the physical tests. If you or a loved one meet these criteria, participating in this study could offer a chance to improve health while waiting for a transplant.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients included in heart transplant list ≤1 month
• • hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg.
• • dobutamine dose ≤ 10 mcg/kg/min
• Exclusion Criteria:
• • heart failure of arrhythmogenic and/or restrictive etiology
• • presence of uncontrolled acute arrhythmias
• • cognitive, orthopedic, or neuromotor changes that prevent functional tests from being carried out