tFUS Induced Transient Scotoma for Individual Dosing
Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · May 17, 2024
Trial Information
Current as of February 18, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new technique called transcranial Focused Ultrasound Stimulation (tFUS). The goal is to see how this method can affect the brain in a measurable way and to find out how different types of visual perception—like seeing something consciously versus reacting without being aware—are influenced by tFUS. Researchers aim to understand the thresholds, or limits, for effective use of this technique in healthy individuals.
To be eligible for the study, participants should be between 18 and 70 years old, have normal or corrected vision and hearing, and not have any neurological or psychological conditions. The study is open to all genders and aims to include a diverse group of participants. Those who join can expect to undergo some assessments related to their vision and brain responses. Importantly, participation is completely voluntary, and strict measures are in place to ensure safety, especially for women who could become pregnant. If you’re interested and meet the criteria, your involvement could contribute to important findings in understanding brain function and visual perception.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Male or female
- • Age 18-70
- • Normal or corrected-to normal vision and hearing
- • No neurological or psychological illness
- Exclusion Criteria:
- • Diagnosis of any depressive or anxiety disorder
- • Diagnosis of schizophrenia or bipolar disorder
- • Current use of any non-prescribed psychoactive medications or drugs
- • Contraindication to enter the MRI environment.
- • Pregnancy (or suspected/possible pregnancy or plan to become pregnant in the short term).
- • Urine Pregnancy Test: If the subject is a woman of childbearing potential and /or a man capable of fathering a child before, during, and/or after participation precaution should be taken. Examples of acceptable methods of birth control for participants involved in the study include: birth control pills, patch, IUD, condom, sponge, diaphragm with spermicide, or avoiding sexual activity that could cause the subject to become pregnant.
- • Inability to adhere to treatment schedule.
- • Initiation of new antidepressant treatment at the time of study randomization.
- • NOTE: There will be no exclusion based upon gender or minority status. We anticipate that at least 50% of the participants will be women. The percentage of minority participants is expected to be at least 5%. We will make vigorous attempts to increase this number by posting advertisement flyers in minority communities.
- • Children, prisoners, and institutionalized individuals will not be recruited, because they are beyond the scope of the objectives. Moreover, we will emphasize that participation in this study is completely voluntary. Recruitment of women and minorities has been addressed above. Non-English speaking subjects will not be recruited because they may not be able to understand instructions, which could undermine the validity of the results.
About Medical University Of South Carolina
The Medical University of South Carolina (MUSC) is a leading academic health center dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on translational medicine, MUSC leverages its extensive resources and expertise to facilitate groundbreaking studies across various medical disciplines. The institution is committed to fostering collaboration among researchers, healthcare professionals, and patients, ensuring that cutting-edge discoveries translate into effective treatments. As a pioneer in health education and research, MUSC plays a vital role in shaping the future of medicine and enhancing health outcomes in the community and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Charleston, South Carolina, United States
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0