A Multimodal Wearable Device-based Study to Evaluate the Efficacy of an Exercise Prescription Intervention in IBD

Launched by PING AN · May 18, 2024

Keywords

ClinConnect Summary

Inflammatory bowel disease (IBD) is a chronic inflammatory bowel disease that mainly involves the digestive system, including Crohn's disease (CD) and ulcerative colitis (UC).CD is characterized by abdominal pain, diarrhea, abdominal mass, fistula formation and intestinal obstruction. CD is characterized by abdominal pain, diarrhea, abdominal mass, fistula formation, and intestinal obstruction; UC is characterized by diarrhea, mucopurulent blood stools, and abdominal pain, and the peak age of onset is between 15 and 40 years old. Notably, many studies have shown that patients with inflammat...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Commitment to comply with the study procedures and cooperate in the implementation of the full study
• • Age ≥ 18 years old, gender is not limited
• • Muscle strength examination of all four limbs is greater than or equal to grade 3
• • Patients with a diagnosis of CD or UC in combination with clinical presentation, laboratory examination, endoscopy, imaging and histopathologic examination, with a disease course in mild to moderate activity or remission
• • Presence of low or high BMI, malnutrition, muscular dystrophy, and anxiety
• • Voluntarily sign a written informed consent
• Exclusion Criteria:
• • Absolute contraindications to exercise: acute stages of various diseases (e.g. cerebral hemorrhage, acute stage of myocardial infarction), severe complications, severe cardiopulmonary dysfunction, severe gastrointestinal problems (e.g. gastric perforation, intestinal obstruction), severe locomotor system disorders (e.g. severe bone fracture), as well as other diseases that are not under effective control
• • Relative contraindications to exercise: severe hypertension, severe diabetes, chronic pain, cardiac arrhythmia, etc
• • Persons with unstable vital signs
• • Presence of cognitive, communication disorders
• • Patients who have recently undergone gastrointestinal surgery (\<1 month) or who have not fully healed
• • Short bowel syndrome
• • Presence of extra-intestinal manifestations and complications that interfere with therapy, such as retinopathy, deep vein thrombosis, etc
• • Pregnant or lactating women
• • Active tuberculosis; if subjects are suspected of having active tuberculosis, chest X-ray, sputum and exclusion by clinical signs and symptoms are required
• • Other potential subjects who are not suitable for participation in this study

Trial Officials