Trials
Search / Trial NCT06428227

Exercise Capacity and Fatigue in Heart Failure Patients With and Without Inspiratory Muscle Weakness

Launched by GAZI UNIVERSITY · May 20, 2024

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Trial Information

Current as of March 13, 2025

Completed

Keywords

Heart Failure Exercise Capacity Respiratory Muscle

ClinConnect Summary

It is believed that respiratory muscle abnormalities develop earlier and more extensively than extremity muscle abnormalities in heart failure. Diaphragm dysfunction contributes to decreased quality of life while simultaneously increasing morbidity and mortality. Inspiratory muscle weakness is observed in 30-50% of patients, with the severity of weakness increasing as the disease progresses. Heart failure patients exhibit increased airway resistance and ventilatory response during exercise. Fatigue and dyspnea are common symptoms associated with exercise intolerance and decreased quality of...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • HF patients were being aged over18 years
  • • clinically stable at least four weeks
  • • having no change in medications over three months
  • • The inclusion criteria for healthy controls were being aged over 18 without a chronic disease
  • Exclusion Criteria:
  • • having unstable angina, acute myocardial infarction, uncontrolled hypertension, significant valvular disease, history of malignancy or orthopedic, rheumatologic, neurological, or pulmonary diseases
  • • The exclusion criteria for the healthy controls were having any chronic or systemic disease, and having physical limitation

Trial Officials

Meral Boşnak Güçlü, Prof. Dr

Study Director

Gazi University

Nihan Katayıfçı, Dr.

Study Chair

Mustafa Kemal University

About Gazi University

Gazi University, a leading research institution based in Ankara, Turkey, is committed to advancing medical knowledge and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university integrates cutting-edge research with clinical practice to explore new therapeutic approaches and enhance existing treatments. Gazi University adheres to the highest ethical standards and regulatory guidelines, ensuring the integrity and safety of its clinical trials. By fostering partnerships with healthcare professionals and academic institutions, Gazi University aims to contribute significantly to the global scientific community and address pressing health challenges.

Locations

Ankara, çankaya, Turkey

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0