Trials
Search / Trial NCT06428890

Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With Elevated and Stage 1 Hypertension

Launched by CALIFORNIA BAPTIST UNIVERSITY · May 20, 2024

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Trial Information

Current as of March 13, 2025

Completed

Keywords

ClinConnect Summary

Muscle metatoreflex (MMR) has been known to play an important role in adjusting hemodynamic responses during exercise. The reflex increases sympathetic activity to heart and blood vessels to increase blood supply to contracting skeletal muscles. On the other hand, studies demonstrated that abnormal cardiovascular responses occurred by the overactive MMR in pathological conditions such as hypertension, diabetes, and congestive heart failure. Excessive blood pressure (BP) responses to exercise induce cardiovascular events such as stroke, heart attack, and coronary artery disease. Previously, ...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • • systolic blood pressure: 120-139 mmHg and/or a diastolic blood pressure: 80-89 mmHg
  • Exclusion Criteria:
  • • taking medications that could affect cardiovascular function or BP

Trial Officials

Jong-Kyung Kim, Ph.D.

Principal Investigator

California Baptist University

About California Baptist University

California Baptist University (CBU) is a reputable institution dedicated to advancing health sciences through innovative research and clinical trials. With a commitment to academic excellence and community service, CBU leverages its state-of-the-art facilities and interdisciplinary collaboration to conduct clinical trials that contribute to the understanding and treatment of various health conditions. The university is focused on fostering an environment of ethical research practices, ensuring participant safety, and promoting evidence-based practices that enhance patient care. Through its clinical trial initiatives, CBU aims to translate scientific discoveries into practical applications that benefit society.

Locations

Riverside, California, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0