Trials
Search / Trial NCT06429332

International Care Bundle Evaluation in Cerebral Hemorrhage Research

Launched by REGION SKANE · May 20, 2024

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Trial Information

Current as of March 13, 2025

Not yet recruiting

Keywords

Intracerebral Hemorrhage Oral Anticoagulant Blood Pressure Lowering Early Intensive Blood Pressure Lowering Care Bundle Implementation Study Reversal Treatment Outcome Uw M Rs Modified Rankin Scale

ClinConnect Summary

Spontaneous intracerebral hemorrhage (ICH) accounts for 10 to 15% of all strokes in high-income countries (HIC), and nearly twice this number in low-income to upper-middle-income countries (LMIC) (29.5%). It is the most devastating type of stroke given the high one-month case fatality of approximately 30-40%, and only 12-39% suffer persistent disability.

Despite several advances in the management of acute ischemic stroke supported by numerous randomized controlled trials (RCT), progress in establishing novel interventions to improve outcomes for ICH has been slow. Still today, the diagnosi...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Adults (age ≥18 years)
  • • Non-contrast computerized tomography (NCCT) imaging-verified diagnosis of spontaneous intracerebral haemorrhage
  • • ≤24 hours from symptom onset or presumed symptom onset (last seen well)
  • Exclusion Criteria:
  • • Previous care limitation
  • • End-stage comorbidity with short life-expectancy (\<6 m; e.g. terminal cancer)
  • • ICH caused by brain tumor or cerebral venous thrombosis
  • • Clinical signs of brain herniation at first presentation (unresponsive patient with bilaterally fixed, maximally dilated pupils)
  • • Pregnant women beyond 22 weeks gestation may only be included after thorough discussion with an obstetrician to determine risks vs benefit.

About Region Skane

Region Skåne is a leading healthcare authority in Sweden, dedicated to advancing medical research and improving patient care through innovative clinical trials. Committed to fostering collaboration between researchers, healthcare professionals, and patients, Region Skåne aims to enhance the understanding of various health conditions and develop effective treatment strategies. With a focus on ethical standards and patient safety, the organization plays a pivotal role in shaping the future of healthcare in the region and beyond, ensuring that clinical trials are conducted with the highest level of scientific rigor and transparency.

Locations

Sydney, , Australia

Malmö, , Sweden

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0