Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.

Launched by CAIRO UNIVERSITY · May 25, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different doses of a medication called intravenous lidocaine can help manage pain during and after surgery. The goal is to see if using lidocaine can reduce the amount of pain patients feel while they recover and lower the chances of having long-lasting pain after surgery. This study is part of a program aimed at improving recovery after surgery.

To participate in this trial, you need to be between 18 and 65 years old and scheduled for specific types of surgeries, such as open surgery for gallbladder removal. You should generally be healthy, without serious liver or kidney issues, and not taking strong pain medications before the surgery. If you join the study, you will receive either lidocaine or a placebo (a substance with no active medication) during your surgery. The trial is currently looking for volunteers, so if you're interested or have questions, it's a good idea to talk to your doctor.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients age between 18 and 65.
• • Patients with ASA I and II status.
• • Patients undergoing open laparotomy surgeries (including open cholecystectomies).
• Exclusion Criteria:
• • Patients unable to comprehend the informed consent.
• • Patients on long term pre-operative opioid regimens.
• • Patients with impairment in hepatic or renal functions.
• • Patients who are planned to receive any form of regional block for the surgery.

Trial Officials