Role of Ultrasound Guide Greater Occipital Nerve Block at Second Cervical Vertebra in Migraine Headache Prophylaxis

Launched by MAHIDOL UNIVERSITY · May 21, 2024

Keywords

ClinConnect Summary

* Neurologist screening candidate volunteers for this study, following the inclusion and exclusion criteria
* Candidate volunteers attended pain clinic for he protocol detail about this research and informed consent
* After signing consent, Volunteers would be stratified randomization into 2 groups between Normal saline and bupivacaine
* Volunteers would be done base line headache diary for 1 month before performing the procedure (Week -4 to week0)
* At Week 0, Volunteers would be applied local anesthetic cream at skin injection site before done the procedure
* According to stratified rando...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18 -65 years old
• • 2. Diagnosis as episodic migraine or chronic migraine and had indication to use migraine prophylaxis
• • 3. Volunteer prefer to use research procedure as first choice of migraine prophylaxis
• • 4. Volunteer already had migraine prophylaxis treatment but still has the one of these following problem 4.1 Frequency of migraine attack more than 4 times/month 4.2 Severe migraine headache \& disturb daily life in spite of using migraine prophylaxis 4.3 Having migraine medication side effect, either from prophylaxis or acute attack medication and cannot titration medication dosage 4.4 migraine attack not improved as using many migraine prophylaxis medications 4.5 Having contra-indication to use prophylaxis migraine medication or standard prophylaxis procedure such as botulinum toxin 4.6 Cannot take prophylaxis medication daily (low compliance) 4.7 Had financial problems in using standard prophylaxis migraine medication or procedure 4.8 Medication overuse headache
• Exclusion Criteria:
• • 1. Had these type of headache in combination with migraine
• • cervicogenic headache
• • occipital neuralgia
• • secondary headache
• • 2. Had contraindication on greater occipital nerve block injection at cervical spine level 2 under ultrasound-guided such as skin infection in needle site
• • 3. Allergy to local anesthetic
• • 4. Uncontrolled psychiatric disorder in 3 months before attending research
• • 5. Cannot understand or reading, writing Thai language

Trial Officials