Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS

Launched by UNIVERSITY MEDICAL CENTER GRONINGEN · May 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment called Transcutaneous Electrical Nerve Stimulation (TENS) on people with Multiple Sclerosis (MS). TENS is a method that sends small electrical signals through the skin to help reduce fatigue and improve walking abilities, which are common challenges for those living with MS. The goal of this study is to better understand how TENS affects brain activity using a special imaging technique called fMRI.

To participate, you need to be between 18 and 65 years old and have a specific level of disability related to MS, measured by a scale called EDSS (with a score less than 7). Unfortunately, not everyone can join; for example, you cannot have certain medical implants, weigh over a certain amount, or have other serious health conditions. If you are eligible and choose to participate, you can expect to undergo some tests to see how TENS affects your brain and symptoms. This research could help improve treatments for MS in the future!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age: 18-65 years
• • EDSS score \< 7
• Exclusion Criteria:
• • metal or electrical implants
• • BMI \> 40
• • claustrophobia
• • being pregnant
• • having a psychiatric disorder
• • having cognitive or communication problems which reduces the capacity to understand instructions
• • having a neurological disorder other than MS
• • having cardiac arrhythmia