Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

Launched by WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY · May 22, 2024

Keywords

ClinConnect Summary

The human gastrointestinal tract hosts a diverse microbial community that has a role in influencing the host's pathophysiological responses. Although there is an abundance of metagenomic data available, the functional dynamics of the gut microbiota still need exploration in different conditions. The microbiota produces various metabolites from dietary products, impacting both host health and pathophysiological functions. The metabolites produced by different microbiota may selectively suppress or stimulate the growth of some components of the gut microbiome, ultimately influencing the dynam...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female adults over the age of 18 years
• Exclusion Criteria:
• • History of a diagnosis of any gastrointestinal condition, such as inflammatory bowel syndrome or disease
• • Antibiotic usage within the past two weeks
• • Antifungal usage within the past month
• • Allergy to L-Phenylalanine or individuals with phenylketonuria (PKU)
• • Adults taking medications known to interact with L-phenylalanine supplements, such as Monoamine Oxidase Inhibitors (MOAI), L-DOPA, and some antipsychotic drugs (complete and extensive drug list will be provided to interested participants during screening)
• • Pregnant or nursing women

Trial Officials