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Search / Trial NCT06434701

Severe COVID-19 Infection in Children Presenting to EDs in Israel and England

Launched by HADASSAH MEDICAL ORGANIZATION · May 29, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying severe COVID-19 infections in children who visit emergency departments (EDs) in Israel and England. Even though COVID-19 is less of a threat now, it's important to keep track of how it affects kids, especially those with severe cases. The goal is to learn more about how severe COVID-19 and related conditions, like multisystem inflammatory syndrome in children (MIS-C), impact young patients and to help health officials make better decisions about managing the virus.

Children aged 16 years or younger who have a severe COVID-19 infection, confirmed by a special test, may be eligible for this study. This includes those who need extra oxygen support or are admitted to intensive care. Participants will be monitored in the hospital to collect important information about their health and recovery. By joining this study, families can help improve understanding and treatment of COVID-19 in children, contributing to better future care and safety measures.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. SACI
  • Patients aged 16 years or younger with a positive COVID-19 PCR nasopharyngeal swab testing or bronchoalveolar sample who meet the definition of SACI:
  • Receive oxygen via low-flow nasal cannula or oxygen mask, high-flow nasal cannula, bilevel or continuous positive airway pressure machine, mechanical ventilation, or extracorporeal membrane oxygenation (ECMO) Or
  • Admitted to ICU
  • 2. MIS-C Patients aged 16 years or younger diagnosed with MIS-C

About Hadassah Medical Organization

Hadassah Medical Organization (HMO) is a leading healthcare institution based in Jerusalem, Israel, renowned for its commitment to advancing medical research and improving patient care. As a prominent clinical trial sponsor, HMO leverages its state-of-the-art facilities and multidisciplinary expertise to conduct innovative research across various therapeutic areas. The organization is dedicated to fostering collaboration between clinical researchers, healthcare professionals, and academic institutions, ensuring the highest standards of ethical practice and scientific rigor. HMO's mission is to translate groundbreaking research into effective treatments, ultimately enhancing health outcomes for diverse populations both locally and globally.

Locations

Jerusalem, , Israel

Tel Hashomer, , Israel

Kfar Saba, , Israel

Jerusalem, , Israel

Afula, , Israel

Be'er Sheva, , Israel

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported