Severe COVID-19 Infection in Children Presenting to EDs in Israel and England
Launched by HADASSAH MEDICAL ORGANIZATION · May 29, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying severe COVID-19 infections in children who visit emergency departments (EDs) in Israel and England. Even though COVID-19 is less of a threat now, it's important to keep track of how it affects kids, especially those with severe cases. The goal is to learn more about how severe COVID-19 and related conditions, like multisystem inflammatory syndrome in children (MIS-C), impact young patients and to help health officials make better decisions about managing the virus.
Children aged 16 years or younger who have a severe COVID-19 infection, confirmed by a special test, may be eligible for this study. This includes those who need extra oxygen support or are admitted to intensive care. Participants will be monitored in the hospital to collect important information about their health and recovery. By joining this study, families can help improve understanding and treatment of COVID-19 in children, contributing to better future care and safety measures.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. SACI
- Patients aged 16 years or younger with a positive COVID-19 PCR nasopharyngeal swab testing or bronchoalveolar sample who meet the definition of SACI:
- • Receive oxygen via low-flow nasal cannula or oxygen mask, high-flow nasal cannula, bilevel or continuous positive airway pressure machine, mechanical ventilation, or extracorporeal membrane oxygenation (ECMO) Or
- • Admitted to ICU
- • 2. MIS-C Patients aged 16 years or younger diagnosed with MIS-C
About Hadassah Medical Organization
Hadassah Medical Organization (HMO) is a leading healthcare institution based in Jerusalem, Israel, renowned for its commitment to advancing medical research and improving patient care. As a prominent clinical trial sponsor, HMO leverages its state-of-the-art facilities and multidisciplinary expertise to conduct innovative research across various therapeutic areas. The organization is dedicated to fostering collaboration between clinical researchers, healthcare professionals, and academic institutions, ensuring the highest standards of ethical practice and scientific rigor. HMO's mission is to translate groundbreaking research into effective treatments, ultimately enhancing health outcomes for diverse populations both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Jerusalem, , Israel
Tel Hashomer, , Israel
Kfar Saba, , Israel
Jerusalem, , Israel
Afula, , Israel
Be'er Sheva, , Israel
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported