Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral Neuromodulation

Launched by UNIVERSITY HOSPITAL, LILLE · May 23, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how stimulating a specific part of the nervous system, called the sacral nerve, can help people with overactive bladder (OAB) symptoms. OAB can cause sudden urges to urinate, frequent trips to the bathroom, and sometimes leaking urine. The researchers want to understand better how this nerve stimulation affects the body’s nervous system and to create a tool that could predict how well this treatment will work for individuals.

To be eligible for the study, you must be at least 18 years old and have been diagnosed with OAB. Participants should be ready for a specific type of treatment called sacral neuromodulation (SNM) and should agree to follow all study procedures. If you join the trial, you can expect to undergo the treatment under general anesthesia. It’s important to note that certain recent treatments or conditions, such as pregnancy or specific medical procedures, may prevent you from participating. The trial is not yet recruiting, so keep an eye out for updates if you’re interested!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male of female ≥ 18 years
• • OAB syndrome
• • Indication for a two-staged SNM
• • Under general anaesthesia with Remifentanil and Propofol
• • Patient who has given written consent to participate in the trial
• • Patient willing to comply with all study procedures and duration
• Exclusion Criteria:
• • Tibial neuro-stimulation (last 3 months)
• • Sacral neuromodulation (last 3 months)
• • Botulinum toxin A intra-detrusor injection (last 9 months)
• • Pregnancy in progress
• • Administrative reasons
• • Guardianship/curatorship