Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD

Launched by THE SECOND HOSPITAL OF NANJING MEDICAL UNIVERSITY · May 23, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a surgical technique called Retrograde Inferior Vena Cava Perfusion (RIVP) and how it might help patients with a serious heart condition known as Acute Type A Aortic Dissection (ATAAD). This condition requires immediate surgery to repair the blood vessels, but the surgical process can sometimes lead to problems in the gastrointestinal (GI) system, which includes our stomach and intestines. The study aims to see if using RIVP during surgery can reduce complications and improve GI function after the operation compared to a standard technique.

To participate in this trial, you must be between 18 and 70 years old and be undergoing surgery for ATAAD. You also need to give your consent to join. The study will involve gathering information about your health before, during, and after the surgery to understand the effects of RIVP better. If you decide to participate, you'll be grouped based on what your doctors recommend, and your health information will be collected in a way that keeps your privacy protected. The researchers hope that the findings will provide valuable insights into improving recovery for patients undergoing this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients undergoing ATAAD repair under CPB.
• • 2. Age: 18-70 years
• • 3. Give consent
• Exclusion Criteria:
• • 1. Variables that can influence gut microbiome like antibiotics or probiotics 2 weeks prior to surgery
• • 2. On chemotherapy
• • 3. Evidence of pre-operative malperfusion of the GI system
• • 4. Presence of GI any pathology (IBD,GERD,PU)
• • 5. Continuous enteral feeding prior to surgery
• • 6. Refuse to participate in the study