Effects of Ingesting Multiple Boluses of Collagen on Muscle & Skin Connective Protein Synthesis in Vivo in Humans

Launched by MAASTRICHT UNIVERSITY MEDICAL CENTER · May 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how consuming collagen protein can affect the production of proteins in our muscles and skin. Collagen is an important part of connective tissues, which help keep our muscles, skin, and other parts of our body strong and healthy. The researchers want to find out if taking multiple doses of collagen peptides (small pieces of collagen) after exercise can boost the creation of these important proteins in humans.

The study will involve 20 healthy young men between the ages of 18 and 35 who are physically active. Participants will do some resistance exercises and then drink either a collagen supplement or a non-caloric placebo (a simple flavored water) that contains vitamin C. Throughout the study, they will be monitored to see how well their bodies are producing muscle and skin proteins. To be eligible, participants must be in good health, not have any serious medical conditions, and should not be taking certain medications. This study is not yet recruiting, but it aims to provide valuable insights into how dietary collagen can help improve muscle and skin health.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Aged between 18-35 years
• • Male
• • Healthy, recreationally active (participating in recreational sports activities ≥ 1 and ≤ 6 h per week, with a maximum of 2 h resistance-type exercise)
• • 18.5 ≤ BMI ≤ 30 kg/m2
• • No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner).
• Exclusion Criteria:
• • Female
• • Smoking
• • Musculoskeletal disorders
• • Metabolic disorders
• • Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications).
• • Chronic use of gastric acid suppressing medication or anti-coagulants
• • Unstable weight over the last three months
• • Diagnosed GI tract disorders or diseases
• • Blood donation in the past 2 months