Effect of Oxycodone on Anxiety State in Painless Abortion

Launched by RUIJIN HOSPITAL · May 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how two different types of anesthesia affect anxiety and depression after a painless abortion. Specifically, the researchers want to compare the effects of a combination of propofol and fentanyl against a combination of propofol and oxycodone. The goal is to see if one option leads to lower anxiety and depression scores after the procedure for women aged 18 to 45 who are in their first trimester of pregnancy.

To be eligible to participate, women must be between 18 and 45 years old, be within 6 to 12 weeks of pregnancy, and be in generally good health (classified as ASA Grading I-II). Participants will receive one of the two types of anesthesia during their procedure and will be asked to complete some simple questionnaires about their feelings of anxiety and pain afterward. It's important to know that individuals with allergies to the study drugs, pre-existing anxiety or depression, or certain health conditions may not qualify for this trial.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age 18-45 years old
• • Gestational age 6-12 weeks
• • American Society of Anesthesiologists （ASA） Grading I-II
• • Fluent communicator and able to complete self-rating scales on her own
• • Voluntarily participate and sign the informed consent form
• Exclusion Criteria:
• • Patients who are allergic to anesthetic drugs such as propofol, oxycodone, fentanyl, etc., or who have had other anesthetic adverse events
• • Patients with anxiety or depression
• • Presence of organic mental disorders, mental retardation
• • Severe acute and chronic infection, severe heart, liver and kidney insufficiency
• • Patients with complications or bleeding \> 50ml during surgery