Genomic Risk in Retroperitoneal Sarcoma

Launched by FOX CHASE CANCER CENTER · May 28, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating the genetic factors that may be linked to the recurrence of retroperitoneal liposarcoma, a type of cancer that develops in the soft tissues behind the abdominal organs. The researchers believe that the fat tissue around the tumor might contain hidden genetic changes that increase the risk of the cancer coming back. By taking samples of this fat from different areas, both near and far from the original tumor, they aim to better understand these underlying factors.

To participate in this study, adults aged 18 and older who have been diagnosed with retroperitoneal liposarcoma and are planning to have surgery for this condition may be eligible. Participants will need to provide consent to join the study. If you join, you can expect to have samples taken during your surgery for genetic testing. This research could help improve future treatments and understanding of this type of cancer. It’s important to note that people with certain past surgeries that make it hard to take fat samples safely may not be able to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients (age ≥18 years).
• • Histologically confirmed retroperitoneal liposarcoma via preoperative biopsy, or cross-sectional imaging suspicious for liposarcoma with planned surgical resection
• • Will be undergoing surgical resection for treatment of primary or recurrent disease
• • Have provided informed consent to participate in this study
• Exclusion Criteria:
• • • Prior surgical anatomy which makes sampling of remote areas of the retroperitoneum technically impossible or clinically undesirable for safety reasons