Hypoferritinemia Without Anemia Among Reproductive Age Females

Launched by AKRAM MEDICAL COMPLEX · May 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a condition called hypoferritinemia without anemia (HWA), which means having low iron levels without being anemic (having low hemoglobin). The study aims to find out which treatment works best for women aged 18 to 45 who have symptoms related to low iron, such as fatigue, poor memory, and hair loss. Participants will be randomly divided into three groups: one group will receive daily oral iron supplements, another group will receive iron through an intravenous (IV) infusion, and the third group will continue with their normal diet without any treatment. After four months, the researchers will check how these treatments affected iron levels and the severity of symptoms.

To be eligible for the trial, participants must be women aged 18 to 45 who show signs of low iron but have normal hemoglobin levels. They need to agree to participate and not have any other health conditions that could interfere with the study. Throughout the trial, participants will visit the clinic once a month for assessments and to receive their treatments. This study is currently active but not recruiting new participants. It's an important step in understanding how to effectively manage low iron levels and improve the health of women experiencing these symptoms.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Reproductive age females: 18 to 45 years
• • Clinical symptoms of iron deficiency which are fatigue/ tiredness, poor work productivity, poor attention and memory loss, sore tongue, poor condition of skin, nails or hair, including hair loss, delayed skin wound healing, palpitation and restless leg syndrome
• • Normal CBC: hemoglobin level12mg/dl and above
• • Serum ferritin levels: below 30 ng/ml
• • Normal thyroid levels
• • Normal blood sugar levels
• • Willing and able to sign informed consent
• Exclusion Criteria:
• • Males
• • Post-menopausal
• • Premature menopause
• • Anemic Females: hemoglobin levels i.e. less than 12 g/dl
• • Serum ferritin level above 30 ng/ml.
• • Disturbed thyroid levels
• • Disturbed blood sugar levels
• • Pregnant
• • Lactating
• • Blood donors
• • Co-morbidities i.e., celiac disease, hemorrhoids, malignancies, hematuria, ulcers, heart failure, renal failure, chronic gastric symptoms/ gastric ulcers, chronic liver disease, disturbed thyroid levels and diabetes
• • Any medication or supplement which may impact iron metabolism.
• • History of iron or multivitamins supplementation in the last 3 months