Nutritional Intervention for Sustaining Health (NURISH) Trial

Launched by UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · May 24, 2024

Keywords

ClinConnect Summary

The purpose of this study is to understand how a healthy diet is related to thinking ability and heart health. Participants will be asked to consume a microwaveable study meal or prepackaged smoothie every day for 12 weeks. These meals will be delivered to participant homes using Daily Harvest meal delivery service. The study meals and smoothies will follow either a dietary pattern thought to improve brain and heart health (MIND), or a control diet, and will include foods commonly found in grocery stores. Participants will not know which diet they are assigned to (active or control). Partic...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 45-64 years of age
• • 20/20 or corrected vision
• • No food allergies or intolerances
• • Not pregnant, lactating, or have given birth in the past 12 months
• • Do not smoke, use tobacco, or abuse drugs
• • Absence of liver or gastrointestinal diseases (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, and cancer
• • Not currently taking oral hypoglycemic agents, or insulin
• • No history of malabsorptive or bariatric surgery
• • Cognitively intact with no prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and/or Asperger's syndrome)
• • Able to consume the study meals
• • Not enrolled in another dietary, exercise, or medication study during the study
• Exclusion Criteria:
• • Non-consent of participant
• • Above 64 or below 45 years of age
• • Vision not 20/20 or corrected
• • Food allergies or intolerances
• • Pregnant, lactating, or have given birth in the past 12 months
• • Smoke, use tobacco, or abuse drugs
• • Prior diagnosis of liver or gastrointestinal disease (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, or cancer
• • Currently taking oral hypoglycemic agents or insulin
• • History of malabsorptive or bariatric surgery
• • Cognitively impaired and/or prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and/or Asperger's syndrome)
• • Unable to consume the study meals
• • Concurrent enrollment in another dietary, exercise, or medication study

Trial Officials