Trials
Search / Trial NCT06437925

Effects of Probiotic Ayran on Gingivitis

Launched by CUKUROVA UNIVERSITY · May 29, 2024

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Trial Information

Current as of March 13, 2025

Completed

Keywords

ClinConnect Summary

The most used and studied probiotics in the periodontal literature are lactobacillus and bifidobacterium. The current study aims to observe the effects of daily ayran consumption containing a probiotic combination of Lactobacillus acidophilus and Bifidobacterium bifidum on plaque development and gingival inflammation in an experimental gingivitis model of healthy individuals. The null hypothesis of this study using of probiotics has no additional benefit for periodontal health.

This study evaluates the effects of daily consumption of ayran containing a probiotic combination of Lactobacillu...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Systemic healthy
  • • Subjects with gingivitis defined as a BOP sites ≥ 10% and PD ≤ 3 mm
  • • No radiographic bone loss
  • • Non-smoking participants
  • Exclusion Criteria:
  • • History of using antibiotics or anti-inflammatory drugs or probiotic preparations or food supplements in the last 6 months,
  • • Undergoing orthodontic treatment,
  • • Active carious lesions
  • • Mouth breathing
  • • History of allergy for milk or fermented milk products.
  • • Taking medications affecting the gingiva and/or oral mucosa

Trial Officials

Cenk Haytac, phd

Principal Investigator

Professor Doctor

About Cukurova University

Cukurova University, a prominent institution located in Adana, Turkey, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university fosters a dynamic research environment that promotes the development of new therapies and treatment modalities. Its commitment to ethical standards and patient safety ensures that all clinical trials are conducted with the highest level of scientific rigor. Cukurova University aims to contribute significantly to the global medical community by facilitating groundbreaking studies that address pressing health challenges.

Locations

Adana, , Turkey

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0