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A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth

Launched by FUTURE UNIVERSITY IN EGYPT · May 30, 2024

Trial Information

Current as of February 18, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is investigating a new treatment for patients with a painful condition called irreversible pulpitis, which affects the inner part of mature teeth, specifically the lower permanent first molars. The study is comparing two treatment methods: one that uses a combination of special materials called A-prf and nanochitosan, and another that uses chitosan alone. Researchers want to see which method is more effective in relieving symptoms and improving the health of the tooth.

To be eligible for this trial, participants should be between 15 and 30 years old, and they must have a mature tooth diagnosed with symptomatic irreversible pulpitis. This means the tooth is causing pain and has a positive response to cold tests. Participants should also be in good overall health, free from diseases that could affect healing, and must be willing to commit to follow-up visits for six months. If you or someone you know meets these criteria and is interested in helping advance dental treatments, this study might be a good option to consider.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.
  • Patients of either gender aged from 15-30.
  • Tooth should give positive response to cold test.
  • Haemostasias should be achieved after total pulpotomy.
  • The tooth is restorable and free from advanced periodontal disease, cracks and splits.
  • Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
  • Patients who will agree to the consent and will commit to follow-up period.
  • Patients with mature root.
  • Patients with no internal or external resorption and no periapical lesions.
  • Soft tissues around the tooth are normal with no swelling or sinus tract.
  • Exclusion Criteria:
  • Patients with immature roots.
  • Haemostasias after 10 minutes can not be controlled after total pulpotomy
  • Patients with any systemic disease that may affect normal healing.
  • Patients with periapical lesions or infections.
  • Pregnant females.
  • Patients who could/would not participate in a 6 months follow-up.
  • Patients with fistula or swelling
  • Patients with necrotic pulp.
  • Patients with old age.

Trial Officials

wael H Kamel, Prof.

Study Director

Future University in Egypt

Hani s sadek, Prof.

Principal Investigator

Future University in Egypt

About Future University In Egypt

Future University in Egypt is a leading academic institution dedicated to advancing medical research and education. As a clinical trial sponsor, the university focuses on innovative studies that aim to enhance healthcare outcomes and address pressing medical challenges. With a commitment to ethical standards and scientific rigor, Future University collaborates with healthcare professionals and researchers to facilitate evidence-based practices and contribute to the global body of medical knowledge. Its strategic initiatives aim to foster a culture of research excellence, ultimately benefiting both local and international communities.

Locations

Cairo, Fifth Settlement, Egypt

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0