Optimizing Bronchopulmonary Cancer Screening

Launched by INSTITUT CURIE · May 28, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how well a special type of scan called a thoracic scanner can be used to screen for bronchopulmonary cancer, which affects the lungs and airways. The study is taking place in France and aims to see if this screening can be done effectively within a structured network of healthcare centers. They are currently recruiting participants who are between 50 and 74 years old, live in the Île-de-France region, and are either current smokers or have quit smoking within the last 10 years, with a significant smoking history.

To be eligible for the trial, participants must have a history of heavy smoking and be willing to join a program to help quit if they still smoke. However, those with current symptoms of bronchopulmonary cancer, a recent CT scan of the chest, or other severe health issues cannot participate. If you join the trial, you can expect to undergo a screening scan and possibly receive support for quitting smoking. This study is important because it seeks to improve early detection of lung cancer, which can lead to better treatment outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participant aged 50 to 74.
• • Resident in the Île-de-France region.
• * Active smoker or quit smoker for 10 years or less:
• • 1. more than 10 cigarettes a day for more than 30 years,
• • 2. more than 15 cigarettes a day for more than 25 years.
• • The participant has been informed and has signed the consent form.
• • Social Security System affiliation.
• • Willingness to participate in a smoking cessation program, if currently smoking.
• Exclusion Criteria:
• • Active cancer or a history of cancer in remission for less than 5 years (except basal cell carcinoma of th skin or epithelioma in situ of the uterine cervix).
• • Presence of symptoms suggestive of bronchopulmonary cancer. Participants with these symptoms require immediate diagnostic investigations and are therefore not eligible for screening.
• • Weight \>= 140 kg.
• • Severe comorbidity contraindicating therapeutic options or invasive thoracic diagnostic investigations.
• • Inability to climb two flights of stairs without stopping.
• • A thoracic CTscan performed within the previous year.
• • Persons deprived of liberty or under guardianship.
• • Impossibility to undergo the medical monitoring of the trial for geographical, social or psychological reasons.