Trials
Search / Trial NCT06440161

Association of Intraoperative Haemodynamic and Postoperative Complications in Type A Aortic Dissection Surgery

Launched by NANJING FIRST HOSPITAL, NANJING MEDICAL UNIVERSITY · May 28, 2024

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Trial Information

Current as of March 14, 2025

Completed

Keywords

Acute Kidney Injury Intraoperative Hypotension Venous Congestion Acute Kidney Disease Type A Aortic Dissection

ClinConnect Summary

Type A aortic dissection (TAAD) is a catastrophic cardiac macrovascular disease with a striking in-hospital mortality rate of 22%-31%. Among the myriad of complications following TAAD surgeries, acute kidney injury (AKI) is one of the most prevalent, boasting an incidence of 40-55%. Notably, this incidence surpasses that observed in other cardiovascular procedures, such as coronary artery bypass grafting (CABG), which ranges from 10-20%, and aortic valve replacement (AVR) at 17-23%. Furthermore, the occurrence of AKI post-TAAD surgeries has been linked with escalated in-hospital, short-term...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • 1) Eligible patients were adults, aged 18 or older.
  • Exclusion Criteria:
  • • 1. Lacking preoperative serum creatinine (Scr) values
  • • 2. Insufficient hemodynamic or laboratory data
  • • 3. Exhibiting a preoperative Scr level ≥133 μmol/L
  • • 4. Patients with renal insufficiency before surgery
  • • 5. Patients on preoperative dialysis

Trial Officials

Ya-li Ge

Study Director

The First Affiliated Hospital with Nanjing Medical University

About Nanjing First Hospital, Nanjing Medical University

Nanjing First Hospital, affiliated with Nanjing Medical University, is a leading medical institution dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on patient-centered care and cutting-edge medical practices, the hospital serves as a key player in the development of new therapies and treatment protocols. Its collaborative environment fosters interdisciplinary research, enabling the integration of scientific inquiry with clinical application. Nanjing First Hospital is committed to improving health outcomes and contributing to the global medical community through rigorous trial design and execution, ensuring the highest standards of ethical practice and patient safety.

Locations

Nanjing, Jiangsu, China

Nanjing, Jiangsu, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0