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Search / Trial NCT06440512

The Effect of Chocolate on Vascular Function of Endurance Runners

Launched by ARISTOTLE UNIVERSITY OF THESSALONIKI · May 31, 2024

Trial Information

Current as of July 27, 2025

Not yet recruiting

Keywords

Arterial Stiffness Aerobic Fitness Chocolate Polyphenols Endurance Runners

ClinConnect Summary

This clinical trial is looking at how chocolate affects the blood vessels of endurance runners. Specifically, it will compare the effects of dark chocolate and white chocolate on male runners. The study aims to find out if eating chocolate can help improve how well these runners’ blood vessels function during exercise.

To participate, men aged 25 to 55 who are healthy and regularly run at least three times a week can apply. However, people with certain health conditions, such as heart disease, diabetes, or those who are allergic to chocolate, won't be able to join. If selected, participants will need to come in for research sessions on specific days and will be asked to eat both types of chocolate during the study. This research is not yet recruiting participants, so there’s still time to learn more before the study begins.

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • Gender: Male
  • Age: 25-55 years
  • Healthy status
  • Active endurance runner
  • Regular physical activity (at least 3 times per week)
  • Availability on specific days and times for research sessions
  • Willingness and consistency
  • Exclusion Criteria:
  • Allergies or Intolerances: Participants with known allergies or intolerances to chocolate or any of its ingredients.
  • Cardiovascular Diseases: Participants with known cardiovascular diseases or history of cardiac episodes.
  • Metabolic Disorders: Individuals with diabetes or other metabolic disorders that may affect glucose and insulin metabolism.
  • Contradictory Diet: Individuals following specific diets that may affect the study, such as high or low flavonoid diets.
  • Medication Use: Individuals taking medications that affect vascular function, such as antihypertensives or anticoagulants.
  • Smoking: Smokers or individuals who have quit smoking within the last six months.
  • Substance Abuse: Individuals with a history of alcohol or substance abuse.
  • Patients with Chronic Diseases: Individuals with serious chronic diseases that may affect the study outcomes.
  • Participation in Other Studies: Individuals participating in other clinical trials or research that may affect the study outcomes.
  • Physical Condition: Individuals who are not regular runners or who do not exercise regularly at a level similar to other participants.

About Aristotle University Of Thessaloniki

Aristotle University of Thessaloniki (AUTH) is a prestigious institution in Greece, renowned for its commitment to advancing knowledge and innovation in the field of clinical research. As a leading academic sponsor of clinical trials, AUTH leverages its extensive resources and expertise to conduct rigorous studies that contribute to the understanding of various medical conditions and the development of novel therapeutic interventions. The university fosters collaboration among multidisciplinary teams, ensuring adherence to the highest ethical standards and regulatory requirements while promoting scientific excellence and enhancing patient care.

Locations

Thessaloniki, , Greece

Patients applied

0 patients applied

Trial Officials

Evangelia Kouidi, Professor

Principal Investigator

Aristotle University Of Thessaloniki

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported