Effect of Lifestyle Intervention on Mobilization of Fat Storage and Iron Deposition in Obesity
Launched by THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY · May 28, 2024
Trial Information
Current as of March 14, 2025
Completed
Keywords
ClinConnect Summary
Fat mobilization status is assessed using magnetic resonance, while the relief of glucose metabolism is determined based on the results of the OGTT before and after life style intervention.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • age between 18 and 80 years
- • have a BMI greater than 28.0 kg/m2
- • exhibit abdominal obesity, defined as a waist circumference of at least 90 cm for men and 85 cm for women
- • willing to undergo a 6-month lifestyle intervention
- Exclusion Criteria:
- • a prior history of pancreatic diseases;
- • combination of drug-induced hepatitis, autoimmune hepatitis, and viral hepatitis;
- • with a definitive diagnosis of diabetes who have already started medication treatment;
- • severe complications from type 2 diabetes or other significant diseases;
- • usage of drugs affecting body weight, insulin sensitivity, or metabolic-associated fatty liver disease in the past three months (such as insulin, glucocorticoids, thiazolidinediones, metformin, SGLT-2 inhibitors, or GLP-1 receptor agonists);
- • with malignant tumors;
- • acute or chronic infection;
- • hemochromatosis;
- • alcohol dependence, defined as ethanol intake exceeding 140 g/week for men and 70 g/week for women.
Trial Officials
Ping Jin
Study Chair
The Third Xiangya Hospital of Central South University
About The Third Xiangya Hospital Of Central South University
The Third Xiangya Hospital of Central South University is a leading academic medical institution in China, dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital focuses on a wide range of medical disciplines, emphasizing patient-centered approaches and evidence-based practices. With a commitment to improving treatment outcomes and enhancing patient care, the hospital collaborates with a diverse network of researchers and healthcare professionals, aiming to contribute significantly to the global medical community through rigorous scientific inquiry and high-quality clinical studies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Changsha, Hunan, China
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0