Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine

Launched by APPLIED SCIENCE & PERFORMANCE INSTITUTE · May 29, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two different types of caffeine: an extended-release version (ER-CAFF) and an immediate-release version (IR-CAFF). Researchers want to see how these types of caffeine impact mood, alertness, and cognitive (thinking and memory) abilities, especially after a night of poor sleep. The study will involve healthy men and women between the ages of 35 and 50 who usually consume moderate amounts of caffeine. Participants will be asked to have less than five hours of sleep before coming to the lab for two visits, where they will take either type of caffeine and undergo various tests to measure its effects.

To be eligible for the study, individuals should have a body mass index (BMI) between 18.5 and 29.9 and not have a history of anxiety or sleep disorders. Participants will be carefully screened to ensure they meet these criteria. Throughout the study, they'll need to wear a device that tracks their sleep and physical activity. This study is expected to last about two weeks, and there will be a one-week break between the two caffeine types to ensure accurate results. It’s a great opportunity for those who fit the criteria to contribute to research that may help understand how different types of caffeine affect our bodies and minds.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female aged 35-50 years (both limits inclusive);
• • Body mass index (BMI) of 18.50-29.99 kg/m2 -Habitual moderate caffeine consumers (200-400 mg/day) assessed through caffeine assessment tool (Caffeine -
• • Consumption Questionnaire, CCQ);
• • Intermediate chronotype (\>31 or \<69 on Morningness-Eveningness Questionnaire).
• Exclusion Criteria:
• * Subjects presenting any of the following will not be included in the study:
• • No history of anxiety disorders or sleep disorders;
• • Non-smokers;
• • Alcohol consumption 72 hours prior to the start of study/consumption of study product;
• • No use of sleep medicines, melatonin, marijuana within two weeks of start of study;
• • No travel involving time zone change, shift work, or other life events that alter sleep schedule \>3 hours from the norm one week before the start of study (assessed using sleep-wake schedule diary for week prior to study);
• • Caffeine restricted past 12 PM from the day prior to the start of study (verify through caffeine diet history).