Patient Observation With Environmental and Wearable Sensors in Myasthenia Gravis

Launched by HEINRICH-HEINE UNIVERSITY, DUESSELDORF · May 29, 2024

Keywords

ClinConnect Summary

This clinical trial, called "Patient Observation With Environmental and Wearable Sensors in Myasthenia Gravis," is studying how we can better understand and monitor the effects of myasthenia gravis, a condition that affects muscle strength. The researchers will use various digital tools, like smartphone apps and wearable sensors, to track patients’ health and daily activities. By combining this digital information with regular doctor visits and questionnaires about quality of life and sleep, they hope to find better ways to see how well treatments are working and to tailor them to each patient’s needs.

To participate in the trial, you need to be at least 18 years old and have a formal diagnosis of generalized myasthenia gravis or another related syndrome. You also need to be able to use a smartphone with specific software. If you decide to join, you will help researchers gather important data that could improve treatment options for people with myasthenia gravis. It's important to note that if you only have eye symptoms or have other serious health issues, you may not be eligible to take part in the study.

Gender

ALL

Eligibility criteria

• * Formal diagnosis of generalized Myasthenia Gravis, with at least one of the following criteria:
• • Response to oral or intravenous administration of an acetylcholinesterase inhibitor
• • Evidence of pathological decrement/ elevated jitter
• • Evidence of Myasthenia Gravis-typical antibody (AChR, LRP4, MuSK, Titin) OR other diagnosed Myasthenic Syndrome
• • Age ≥ 18
• • Usage of Smartphone with Android 8.1 (or higher) or IOS12.3 (or higher)
• • Able to provide informed consent, based on investigator´s judgment
• Exclusion Criteria:
• Patients who meet any of the following criteria will be excluded from participation:
• • Unable or unwilling to give informed consent
• • Unable or unwilling to use the smartphone app
• • Any significant comorbidity that might potentially interfere with the ability to successfully participate in the study, based on investigator´s judgment
• • Patient with exclusively ocular symptoms (ocular myasthenia gravis)