Trials
Search / Trial NCT06442345

Pneumocystis Jirovecii Genotyping

Launched by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST · May 29, 2024

Trial Information

Current as of February 19, 2025

Not yet recruiting

Keywords

Pcp Genotyping

ClinConnect Summary

We share our lives with microorganisms, and these generally do not pose a problem if an individual is healthy with a normal immune system. However, if the immune system was not functioning properly (e.g., cancer patients), they are at risk of infection. One microorganism, a fungus called Pneumocystis jirovecii (PCP), can cause severe chest infections in patients without properly functioning immune systems, leading to hospitalisation and death if untreated. If patients remain without a functioning immune system, they have a greater chance of repeated infection.

PCP spreads through air from ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Total nucleic acid extracts from adult patients (over 18 years old) with a positive PCP diagnosis (\& detected at \> 50 copies/10ul) from routine respiratory panel testing.
  • Exclusion Criteria:
  • Total nucleic acid extracts from patients with a negative PCP diagnosis from routine respiratory panel testing
  • Total nucleic acid extracts from non-adult patients (under 18 years old).
  • PCP positive total nucleic extract samples with \< 50 copies/10ul.
  • Patients included on the UK National Opt-Out register

About Nottingham University Hospitals Nhs Trust

Nottingham University Hospitals NHS Trust is a leading healthcare provider in the UK, dedicated to delivering high-quality patient care and advancing medical research. Comprising two major hospitals, Queen's Medical Centre and Nottingham City Hospital, the Trust is at the forefront of clinical innovation and education. With a strong emphasis on translational research, Nottingham University Hospitals NHS Trust actively sponsors clinical trials aimed at improving treatment outcomes and understanding various health conditions. The Trust collaborates with academic institutions, healthcare professionals, and industry partners to foster a robust research environment that enhances clinical practice and contributes to evidence-based medicine.

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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