Pneumocystis Jirovecii Genotyping

Launched by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST · May 29, 2024

Keywords

ClinConnect Summary

We share our lives with microorganisms, and these generally do not pose a problem if an individual is healthy with a normal immune system. However, if the immune system was not functioning properly (e.g., cancer patients), they are at risk of infection. One microorganism, a fungus called Pneumocystis jirovecii (PCP), can cause severe chest infections in patients without properly functioning immune systems, leading to hospitalisation and death if untreated. If patients remain without a functioning immune system, they have a greater chance of repeated infection.

PCP spreads through air from ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Total nucleic acid extracts from adult patients (over 18 years old) with a positive PCP diagnosis (\& detected at \> 50 copies/10ul) from routine respiratory panel testing.
• Exclusion Criteria:
• • Total nucleic acid extracts from patients with a negative PCP diagnosis from routine respiratory panel testing
• • Total nucleic acid extracts from non-adult patients (under 18 years old).
• • PCP positive total nucleic extract samples with \< 50 copies/10ul.
• • Patients included on the UK National Opt-Out register