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Search / Trial NCT06442930

EXtubation Related Complications - the EXTUBE Study (EXTUBE)

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Jun 3, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

The EXTUBE Study is an international research project aimed at understanding complications that can happen after removing a breathing tube, which is called extubation. The study focuses on finding out how often these problems occur, what factors might increase the risks, and how patients do after extubation. Researchers will also look at how healthcare teams manage the extubation process, whether it takes place in the operating room, other anesthesia locations, or in the intensive care unit.

To participate in this study, patients need to be adults aged 18 or older who are having their breathing tube removed after surgery or during critical illness. However, those whose extubation is part of stopping life support or having a tracheostomy tube removed will not be included. Participants will be monitored closely during the study, and their experiences will contribute valuable information to improve care for future patients undergoing extubation. If someone is not eligible, the reasons for their exclusion will be shared.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult patients (≥18 years old)
  • Undergoing extubation of an endotracheal tube (including index extubation and re-extubations) after general anesthesia in the OR, out of OR anesthesia location or ICU
  • Undergoing extubation during the specified enrollment window
  • Exclusion Criteria:
  • Patients will be excluded if the extubation is performed in the context of withdrawal of life support measures,
  • Patients will be excluded if the extubation is performed for tracheostomy decannulation
  • For each patient who is not included, reasons for exclusion will be reported.

About University Health Network, Toronto

University Health Network (UHN), based in Toronto, is a leading academic health sciences center dedicated to advancing patient care through innovative research and education. As a prominent sponsor of clinical trials, UHN integrates cutting-edge scientific discoveries with clinical practice, facilitating the development of new therapies and treatment modalities. With a commitment to improving health outcomes, UHN collaborates with a diverse network of researchers, healthcare professionals, and industry partners, fostering an environment that prioritizes patient safety and ethical standards in clinical research. Through its extensive resources and expertise, UHN plays a pivotal role in transforming healthcare and enhancing the quality of life for patients both locally and globally.

Locations

Toronto, Ontario, Canada

Toronto, Ontario, Canada

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Matteo Parotto, MD, PhD

Principal Investigator

UHN

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported