EXtubation Related Complications - the EXTUBE Study (EXTUBE)

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Jun 3, 2024

Keywords

ClinConnect Summary

Globally, over 200 million people each year require extubation. While routinely performed, extubation is a skilled and potentially high-risk procedure that should be performed only when physiologic, pharmacologic, and contextual conditions are optimal. Complications at this stage of patient care can result in decreased oxygen delivery to the brain and body, sometimes leading to serious adverse events such as cardiac arrest, brain damage, or death. Indeed, one quarter of airway complications that result in death or brain death occur at the time of extubation.

Despite the frequency of extuba...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients (≥18 years old)
• • Undergoing extubation of an endotracheal tube (including index extubation and re-extubations) after general anesthesia in the OR, out of OR anesthesia location or ICU
• • Undergoing extubation during the specified enrollment window
• Exclusion Criteria:
• • Patients will be excluded if the extubation is performed in the context of withdrawal of life support measures,
• • Patients will be excluded if the extubation is performed for tracheostomy decannulation
• • For each patient who is not included, reasons for exclusion will be reported.

Trial Officials