Suturing Through-the-scope System Used for Prophylactic Closure of Colonic Post-ESD Defects

Launched by ISTITUTO CLINICO HUMANITAS · Jun 3, 2024

Keywords

ClinConnect Summary

Large superficial colonic polyps are increasingly detected thanks to colorectal cancer screening programs worldwide. ESD is the technique which provides a high-quality resection of these large polyps.

Nevertheless, several adverse events affect ESD, especially in the colon. They could be life-threatening, call for or prolong the hospitalization, require blood transfusion, additional endoscopic or surgical procedures and increase costs.

Thus, preventing these adverse events is an important clinical and medico-economic objective. Endoscopic closure of post-ESD defects could reduce this risk...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient suffering from 30-60 mm colonic polyps with indication of ESD
• • Male or female patients aged \> 18 years' old
• • Patients able to fill in questionnaires written in Italian
• Exclusion Criteria:
• • Failure of endoscopic resection
• • Suspicion of deep submucosal cancer by analysis of pit pattern (KUDO Vn)
• • Polyp involving the appendix deeply (type 2 or 3 according to Toyonaga classification)
• • Polyp inside the ileo-cecal valvula.
• • Rectal lesions

Trial Officials