National, Multicentric Registry Study on Neuroimmunological Diseases in China

Launched by XUANWU HOSPITAL, BEIJING · May 29, 2024

Keywords

ClinConnect Summary

This clinical trial is focused on understanding various neuroimmunological diseases, such as Multiple Sclerosis and Myasthenia Gravis, among others. Researchers aim to create a large group of patients to study how these conditions progress over time. By collecting data from patients with these diseases, the study hopes to improve treatment options and predict outcomes for individuals suffering from these conditions.

If you have been diagnosed with one of the specified diseases at Xuanwu Hospital or are a healthy adult who has undergone a physical examination there, you might be eligible to participate. Those who are pregnant, have other serious neurological or mental health issues, or cannot follow the study's procedures will not be included. Participants can expect regular check-ups and follow-up assessments to monitor their health and the progression of their illness. This study is an important step in improving our understanding and management of neuroimmunological diseases.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients who diagnosed at Xuanwu Hospital, Capital Medical University with any of the following conditions:
• • Multiple Sclerosis (the criteria followed the Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria)
• • NMO Spectrum Disorder (the criteria followed the Diagnosis and Treatment Guidelines for Optic Neuromyelitis Spectrum Disorders in China 2016)
• • Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (the criteria followed the Consensus of Chinese Experts on Diagnosis and Treatment of Anti-Myelin Oligodendrocyte Glycoprotein Immunoglobulin G Antibody-Associated Diseases)
• • Myasthenia Gravis (the criteria followed the Guidelines for the Diagnosis and Treatment of Myasthenia Gravis in China 2020)
• • Autoimmune Encephalitis (the criteria followed the China Expert Consensus on Diagnosis and Treatment of Autoimmune Encephalitis 2017)
• • Acute Disseminated Encephalomyelitis (the criteria are based on the article titled "Acute disseminated encephalomyelitis" 2007).
• • Healthy adults who underwent a physical examination at the Physical Examination Center of Xuanwu Hospital, Capital Medical University
• Exclusion Criteria:
• • Women during pregnancy or lactation.
• • Patients with other neurological diseases or serious mental diseases.
• • Patients with serious liver and kidney function or other important organ dysfunction.
• • Unable to cooperate with follow-up work and venous blood collection due to poor compliance of patients or healthy volunteers, or incomplete clinical and imaging data.