Trials
Search / Trial NCT06443372

GCF Bax and Bcl-xl Levels in Periodontitis

Launched by AYDIN ADNAN MENDERES UNIVERSITY · May 30, 2024

Trial Information

Current as of February 19, 2025

Completed

Keywords

ClinConnect Summary

According to the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions, participants were categorized into three groups:

I. Periodontitis group (n=23), II. Gingivitis group (n=26) III. Periodontally healthy group (n=26)

Clinical periodontal measurements included probing depth (PD), clinical attachment loss (CAL), the dichotomous scoring of bleeding on probing (BOP +/-), gingival index (GI), and plaque index (PI). All clinical parameters were recorded at six points (mesiobuccal, buccal, distobuccal, mesiopalatal/mesiolingual, palatal/lingual, and...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • No history of smoking
  • At least 18 natural teeth (excluding 3rd molars)
  • Exclusion Criteria:
  • Being diagnosed with diabetes mellitus, rheumatoid arthritis, cardiovascular system diseases, endocrine, immunologic, and mucocutaneous disorders
  • Use of antibiotics, antihypertensives immunosuppressive and anti-inflammatory drugs within the past 6 months and topical antiseptic solutions in the last 3 months
  • Having periodontal treatment in the previous year
  • Wearing removable partial dentures or orthodontic appliances
  • Restorative and endodontic therapy requirements
  • Pregnant or nursing women

Trial Officials

Beral Afacan

Principal Investigator

Aydin Adnan Menderes University

About Aydin Adnan Menderes University

Aydin Adnan Menderes University is a leading academic institution based in Turkey, renowned for its commitment to advancing medical research and education. The university actively sponsors clinical trials that aim to explore innovative therapeutic approaches and enhance patient care. With a multidisciplinary team of experts, state-of-the-art facilities, and a dedication to ethical research practices, Aydin Adnan Menderes University fosters a collaborative environment that supports the development of groundbreaking medical solutions, ultimately aiming to improve health outcomes for diverse populations.

Locations

Aydın, , Turkey

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0