GCF Bax and Bcl-xl Levels in Periodontitis
Launched by AYDIN ADNAN MENDERES UNIVERSITY · May 30, 2024
Trial Information
Current as of February 19, 2025
Completed
Keywords
ClinConnect Summary
According to the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions, participants were categorized into three groups:
I. Periodontitis group (n=23), II. Gingivitis group (n=26) III. Periodontally healthy group (n=26)
Clinical periodontal measurements included probing depth (PD), clinical attachment loss (CAL), the dichotomous scoring of bleeding on probing (BOP +/-), gingival index (GI), and plaque index (PI). All clinical parameters were recorded at six points (mesiobuccal, buccal, distobuccal, mesiopalatal/mesiolingual, palatal/lingual, and...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • No history of smoking
- • At least 18 natural teeth (excluding 3rd molars)
- Exclusion Criteria:
- • Being diagnosed with diabetes mellitus, rheumatoid arthritis, cardiovascular system diseases, endocrine, immunologic, and mucocutaneous disorders
- • Use of antibiotics, antihypertensives immunosuppressive and anti-inflammatory drugs within the past 6 months and topical antiseptic solutions in the last 3 months
- • Having periodontal treatment in the previous year
- • Wearing removable partial dentures or orthodontic appliances
- • Restorative and endodontic therapy requirements
- • Pregnant or nursing women
Trial Officials
Beral Afacan
Principal Investigator
Aydin Adnan Menderes University
About Aydin Adnan Menderes University
Aydin Adnan Menderes University is a leading academic institution based in Turkey, renowned for its commitment to advancing medical research and education. The university actively sponsors clinical trials that aim to explore innovative therapeutic approaches and enhance patient care. With a multidisciplinary team of experts, state-of-the-art facilities, and a dedication to ethical research practices, Aydin Adnan Menderes University fosters a collaborative environment that supports the development of groundbreaking medical solutions, ultimately aiming to improve health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Aydın, , Turkey
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0