Trials
Search / Trial NCT06443970

Low and High Flow Suctioning in Intubated Infants

Launched by COLUMBIA UNIVERSITY · May 30, 2024

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Trial Information

Current as of March 12, 2025

Not yet recruiting

Keywords

Cardiorespiratory Disturbances Neonates Exsalta Endotracheal Suctioning

ClinConnect Summary

Respiratory failure in neonates frequently requires mechanical ventilation through an endotracheal tube (ETT). The presence of an ETT inhibits the infant's intrinsic ability to clear endogenous lung secretions effectively with compromised glottic closure and impaired muccociliary function, and thus regular supportive suctioning of the ETT is essential. The benefits of patent airway are evident, but adverse effects may also result from suctioning which are especially deleterious in extremely preterm infants with immature pulmonary and systemic hemodynamic function. These adverse effects incl...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Preterm and term infants with birth weight more than 1000g receiving ETT suctioning
  • Exclusion Criteria:
  • • Infants with cyanotic congenital heart disease and cardiac rhythm disorders (arrythmias) will be excluded from the study.

Trial Officials

Rakesh Sahni, MD

Principal Investigator

Columbia University

About Columbia University

Columbia University, a prestigious Ivy League institution located in New York City, is a leading sponsor of clinical trials dedicated to advancing medical research and improving patient care. With a robust network of research facilities and a commitment to innovation, Columbia University collaborates with a diverse range of healthcare professionals and researchers to explore groundbreaking therapies and treatment methodologies. The university's clinical trials encompass various fields, including oncology, neurology, and public health, aiming to translate scientific discoveries into effective clinical applications. Columbia University is dedicated to maintaining the highest ethical standards and regulatory compliance, ensuring the safety and well-being of trial participants while contributing to the global body of medical knowledge.

Locations

New York, New York, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0