The BEE-Power Study (Boosting Exercise for Excellent Pediatric Blood Pressure)

Launched by ARKANSAS CHILDREN'S HOSPITAL RESEARCH INSTITUTE · Jun 4, 2024

Keywords

ClinConnect Summary

The BEE-Power Study is a clinical trial aimed at finding out which type of exercise—isometric (like squats and planks) or aerobic (like running)—is better for lowering blood pressure in teenagers aged 13 to 17.5 years who have high blood pressure. If your teenager is overweight and has been diagnosed with high blood pressure but is only making lifestyle changes to manage it, they might be eligible to participate in this study.

Participants will attend three visits over the course of about four weeks. During the first visit, their height, weight, and blood samples will be taken, along with some questionnaires about their diet and growth. At the second visit, they will wear a special monitor to measure their blood pressure for 24 hours. Finally, during the third visit, they will take part in a single session of either isometric or aerobic exercise and wear the blood pressure monitor again afterward. This study is currently recruiting and welcomes all teenagers who meet the eligibility criteria. It’s a great opportunity for participants to contribute to research that could help other young people with high blood pressure in the future!

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • Age 13 to less than 18 years old.
• • Excessive weight: BMI percentile ≥ 85th percentile.
• • Exclusion Criteria
• • Asthma that requires daily use of inhalers to keep symptoms under control
• • Asthma that requires use of rescue inhalers (e.g., albuterol) \>2 days per week
• • Exercise induced asthma
• • Autism spectrum disorder (e.g., Autistic disorder, Rett disorder, Asperger disorder, childhood disintegrative disorder, pervasive developmental disorder not otherwise specified (PDD-NOS)
• • Attention deficit hyperactivity disorder (ADHD) treated with medication or unwillingness to discontinue medication 1 day prior to the study visit and during ambulatory blood pressure monitoring.
• • Oppositional defiant disorder (ODD)
• • Epilepsy
• • Cancer
• • Chronic kidney disease
• • Autoimmune diseases (e.g., lupus, thyroiditis, juvenile idiopathic arthritis)
• • Bleeding disorders (e.g., hemophilia)
• • Chronic infections (e.g., HIV, hepatitis B, hepatitis C)
• • Type 2 and type 1 diabetes mellitus.
• • Other pre-existing medical conditions or medications as determined by the investigators to affect the outcomes of interest.
• • Parent/participant refusal to have blood drawn
• • Unwillingness to wear a 24-hour ambulatory blood pressure monitor.
• • Hypertension managed with medication
• • Allergy to latex