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Search / Trial NCT06444945

Effects of Mulligan Mobilization With Movement as Compared to Kaltenborn Joint Mobilization in the Management of Knee Osteoarthritis

Launched by FOUNDATION UNIVERSITY ISLAMABAD · Jun 5, 2024

Trial Information

Current as of September 16, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

This study is a randomized trial comparing two physical-therapy approaches for knee osteoarthritis: Mulligan mobilization with movement (MWM) and Kaltenborn joint mobilization. Both groups will also receive a heating pad and a gentle electrical nerve stimulation (TENS) to help with pain, plus a resistance exercise program. The researchers want to know which method better reduces knee pain and improves movement, daily function, and walking ability, with outcomes assessed over about two weeks.

Who can participate? Adults aged 40–70 with knee osteoarthritis for at least 3 months, whose knee pain is not more than 8 out of 10 and who have knee X‑rays showing grade III OA or less. They must be referred from a rehabilitation department and not have serious health problems, recent knee trauma or surgery, nerve-related leg issues, or recent knee injections. The study is taking place at Foundation University Islamabad in Pakistan and is currently inviting eligible people to join, aiming to enroll about 40 participants. Outcomes measured over the 2‑week period include knee pain (on a 0–100 scale), knee function (KOOS), knee range of motion, stride length, walking speed, leg strength, and how long it takes to perform five sit-to-stand movements.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Individuals aged 40-70 years (Osama et al, 2022)
  • Having KOA history of no less than 3 months
  • Knee pain less than 8/10 on numeric pain rating scale (NPRS).
  • Radiological evidence of grade III or less on Kellgren classification
  • Patients referred from rehab department
  • Exclusion Criteria:
  • Those with signs of serious pathology, such as malignancy, inflammatory disorder or infection.
  • History of trauma or fractures in lower extremity.
  • Signs of lumbar radiculopathy or myelopathy.
  • History of knee surgery or replacement.
  • Receiving intra-articular steroid therapy in the preceding two months.

About Foundation University Islamabad

Foundation University Islamabad (FUI) is a prominent educational institution dedicated to advancing research and innovation in various fields, including clinical sciences. With a commitment to excellence in education and healthcare, FUI fosters a collaborative environment that encourages multidisciplinary research initiatives. The university actively engages in clinical trials aimed at improving patient outcomes and contributing valuable insights to the medical community. Through its state-of-the-art facilities and a team of experienced professionals, Foundation University Islamabad strives to uphold the highest ethical standards in clinical research, ensuring the integrity and reliability of its findings.

Locations

Islamabad, Pakistan

Patients applied

0 patients applied

Trial Officials

Shanza Fatima, DPT

Principal Investigator

Foundation University Islamabad

Muhammad Osama, PHD*

Principal Investigator

Foundation University Islamabad

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported