Tunisian Clinical Registry on Hypoparathyroidism and Pseudo-hypoparathyroidism

Launched by DACIMA CONSULTING · May 31, 2024

Keywords

ClinConnect Summary

The Tunisian Clinical Registry on Hypoparathyroidism and Pseudo-hypoparathyroidism is a study that aims to gather information about patients who have issues with their parathyroid hormone, which helps regulate calcium levels in the body. Specifically, it looks at two conditions: hypoparathyroidism, where the body does not produce enough of this hormone, and pseudo-hypoparathyroidism, where the body is unable to respond properly to it. This study will collect data on the health, laboratory results, and treatments of these patients in Tunisia.

To participate, individuals must have hypoparathyroidism, which is defined by low calcium levels in the blood along with low or normal parathyroid hormone levels. However, those who have had recent neck surgery, temporary forms of low parathyroid hormone activity, or other specific causes of low calcium levels, such as vitamin D deficiency or chronic kidney disease, will not be eligible. Since the study is observational, participants will be asked to provide information about their condition, but there will be no new treatments or interventions given. This study will help improve understanding of these conditions and potentially guide better care in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Hypoparathyroidism defined by low serum calcium \< 2.2 mmol/l (\< 88 mg/l) associated with inadequate PTH (low or normal) and normal creatinine
• Exclusion Criteria:
• • Cervical surgery \< 6 months.
• • Transient (neonatal, etc.) or functional (dysmagnesemia, etc.) hypoparathyroidism.
• • Other causes of hypocalcemia: vitamin D deficiency, chronic renal failure, etc.
• • Familial hypocalcemia hypercalciuria.
• • Pseudo-pseudo-hypoparathyroidism.