Trials
Search / Trial NCT06445127

Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)

Launched by JOHNS HOPKINS UNIVERSITY · May 31, 2024

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Trial Information

Current as of March 13, 2025

Recruiting

Keywords

Lupus Kidney Disease In Lupus Renal Disease In Lupus Lupus Sle Lupus And Kidneys Lupus Nephritis Protein In Urine Inflammation In The Kidney In Patients With Lupus Lupus And Kidney Impairment

ClinConnect Summary

This clinical trial is looking at whether a special type of scan called Magnetic Resonance Imaging (MRI) can help doctors diagnose kidney problems in patients with systemic lupus erythematosus (SLE), a condition that can affect various parts of the body, including the kidneys. The study aims to see if this non-invasive imaging technique can provide useful information about lupus nephritis, which is inflammation of the kidneys caused by lupus.

To participate in the trial, you need to be an adult over 18 years old who has been diagnosed with SLE and is able to have an MRI. Unfortunately, some people cannot join if they have certain medical devices or conditions, like having a pacemaker, being pregnant, or receiving kidney dialysis. If you decide to participate, you can expect to have one to four kidney MRIs over a six-month period, with each scan taking between 30 to 60 minutes. This trial is currently recruiting participants, and it could help improve how doctors diagnose and treat kidney issues related to lupus.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Male and female adults over the age of 18 who have been diagnosed with SLE and are able to undergo a kidney MRI.
  • Exclusion Criteria:
  • • The participant cannot take part in the study if they have any contraindications to MRI as specified by the current clinical MRI screening protocols including: metallic foreign objects within the body, programmable shunt/shunt, epidural or Swan Ganz catheter, ear or cochlear implant, eye implant, aneurysm clip, pacemaker/wires, internal defibrillator, tissue expander, recent stent placement, blood vessel coil, tracheostomy, stimulator/wires, infusion pump, penile prosthesis, intra-uterine device (IUD), surgical clips, bullets/pellets/bullet ball (BB), medication patch, tattoo, artificial limb, history of welding or metal fragments in eyes, pregnancy, claustrophobia, requirement of conscious sedation or anesthesia, colonoscopy procedure in the last 8 weeks.
  • • Any patient that is receiving renal dialysis.
  • • Any patient that has undergone a renal transplant.

Trial Officials

Homa Timlin, MD, MSc, MRCP, CCST

Principal Investigator

Johns Hopkins School of Medicine

About Johns Hopkins University

Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.

Locations

Baltimore, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0