Outcome of GATT Combined With Goniosynechiolysis in Glaucoma Patients With Secondary Synechial Angle Closure.
Launched by KASR EL AINI HOSPITAL · Jun 5, 2024
Trial Information
Current as of July 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new surgical approach for patients with a specific type of glaucoma called secondary synechial angle closure glaucoma. The goal is to see if combining two procedures—gonioscopy-assisted transluminal trabeculotomy (GATT) and goniosynechialysis—can help lower the pressure in the eye, which is important for preventing vision loss. This trial is currently looking for participants who have this type of glaucoma and require surgery because their eye pressure is not well controlled with medication.
To be eligible for this trial, participants must have more than 180 degrees of angle closure in their eyes and should not have certain other eye conditions, like neovascular glaucoma or significant retinal issues. Throughout the trial, participants can expect to undergo the combined surgical treatment and will be monitored for how well it helps reduce their eye pressure. This trial is open to all adults, and it aims to provide insights that could improve treatment options for patients with this challenging form of glaucoma.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with secondary synechial angle closure glaucoma
- • Involving more than 180 degrees of the iridocorneal angle
- • Requiring surgery for uncontrolled IOP despite maximum tolerated therapy.
- Exclusion Criteria:
- • Eyes with PACG.
- • Eyes with neovascular glaucoma. (Some apparently stable NVG cases would have remnants of neo-vessels in the angle that are hidden behind the synechiae).
- • Eyes with retinal pathology.
- • Eyes requiring combined phacoemulsification and GATT.
- • Eyes with corneal pathology that can preclude surgery and imaging.
About Kasr El Aini Hospital
Kasr El Aini Hospital, a prestigious medical institution affiliated with Cairo University, is dedicated to advancing healthcare through innovative clinical research. With a commitment to excellence, the hospital serves as a leading sponsor of clinical trials, leveraging its state-of-the-art facilities and a multidisciplinary team of healthcare professionals. The institution focuses on a diverse range of therapeutic areas, aiming to improve patient outcomes and contribute to the global medical community. By fostering collaboration and adhering to the highest ethical standards, Kasr El Aini Hospital plays a pivotal role in the development of new treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Giza, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported