Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity

Launched by HOPITAL MONTFORT · May 31, 2024

Keywords

ClinConnect Summary

Background and rationale: This pilot trial aims to evaluate the feasibility and acceptability of a counselling intervention on physical activity in patients with liver steatosis (primary aim) and changes in molecular outcomes (exploratory aim).

Liver steatosis is the build-up of fat in the form of lipid droplets inside hepatocytes (liver cells). Although it is a form of energy storage, it is considered pathological when more than 5% of hepatocytes demonstrate fat infiltration on a liver biopsy or imaging (ultrasound, magnetic resonance, or computed tomography). Until recently, liver steato...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • \>18 years of age,
• • confirmed MASLD or MASH without cirrhosis
• • access to a computer with an internet connection
• Exclusion Criteria:
• • liver disease from another cause,
• • the existence of cirrhosis on imaging or clinically,
• • weekly alcohol consumption over 50g,
• • having a contraindication to PA without medical clearance (the Get Active questionnaire from the Canadian Society for Exercise Physiology is used to determine if medical clearance is needed),
• • being already enrolled in a supervised exercise intervention or PA behaviour change intervention or currently meeting PA guidelines of 150 mins/week
• • the need for a wheelchair, cane, walker, or other support(s) to move

Trial Officials