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Search / Trial NCT06449157

Chocolate or Sevoflurane: Use of Parosmia to Facilitate More Cooperative Inhalation Inductions in Children

Launched by JOHNS HOPKINS UNIVERSITY · Jun 6, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is exploring how a technique called parosmia, which changes the way children perceive smells, can help make the experience of going under anesthesia less stressful. Many children feel anxious and scared during surgery, especially when they have to breathe in anesthetic gases like sevoflurane, which can have an unpleasant smell. The researchers hope that by using parosmia, they can create a more pleasant smell that encourages children to cooperate better during the induction of anesthesia. This is an important step toward improving children's overall experience in the operating room.

To participate in this study, children aged 5 to 12 years old who are generally healthy (classified as ASA I or II) may be eligible. However, children who need emergency surgery, cannot follow pre-surgery food and drink rules, or have certain medical conditions will not be included. Participants will be closely monitored to see if using parosmia helps reduce their anxiety during the process of getting anesthesia. This trial is currently recruiting, and while it is a small-scale study, the findings could lead to larger studies in the future to better understand how to support children during surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Ages of 5-12 years old
  • American Society of Anesthesiologist physical status classification system (ASA) I and II
  • Patients coming from home
  • Exclusion Criteria:
  • Patients undergoing emergent surgery
  • Patients who have not adequately maintained preoperative nothing per mouth/os (NPO) status
  • Patients with inability to communicate verbally
  • Tracheostomy patients
  • ASA III , IV, V patients

About Johns Hopkins University

Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.

Locations

Baltimore, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Pooja O'Neil, MD

Principal Investigator

Johns Hopkins School of Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported