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Search / Trial NCT06449248

Oral Lichen Planus and Systemical Oncological Comorbidities

Launched by CATHOLIC UNIVERSITY OF THE SACRED HEART · Jun 3, 2024

Trial Information

Current as of July 24, 2025

Completed

Keywords

Oral Lichen Planus Cancer Retrospective Multicenter

ClinConnect Summary

Lichen planus (LP) is a chronic mucocutaneous inflammatory disease of unknown etiology.

In its oral variant, oral lichen planus (OLP) has a reported prevalence ranging from 0.5% to 2.2% in the general population. The disease typically occurs between the ages of 30 and 60. Although the pathogenetic mechanism and the triggering factor remain unknown, an immune-mediated pathogenesis has been hypothesized and the role of some factors such as stress, anxiety, diabetes, other autoimmune diseases, hypertension, intestinal diseases, chronic liver diseases, hypercholesterolemia, infections, contact...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria (Study Group):
  • 1. Patients of both sexes, consecutively enrolled in a 1:2 ratio
  • 2. Age over 18 yo
  • 3. Previous clinical and histological diagnosis of OLP
  • Exclusion Criteria (Study Group):
  • 1. Age under 18 yo
  • Inclusion Criteria (Control Group):
  • 1. Patients of both sexes, consecutively enrolled in a 1:2 ratio
  • 2. Age over 18 yo
  • Exclusion Criteria (Control Group):
  • 1. Age under 18 yo
  • 2. Previous clinical and histological diagnosis of OLP

About Catholic University Of The Sacred Heart

The Catholic University of the Sacred Heart is a prestigious academic institution in Italy, renowned for its commitment to advancing medical research and education. With a strong emphasis on ethical standards and community well-being, the university actively engages in clinical trials that contribute to innovative healthcare solutions. Its multidisciplinary approach leverages expertise from various fields, fostering collaborations that enhance the quality and impact of research. The university is dedicated to improving patient outcomes through rigorous science and compassionate care, aligning with its mission to serve the greater good.

Locations

Roma, , Italy

Patients applied

0 patients applied

Trial Officials

Romeo Patini, Univ. Res.

Study Chair

Catholic University of Sacred Heart - Rome

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported