Oral Lichen Planus and Systemical Oncological Comorbidities
Launched by CATHOLIC UNIVERSITY OF THE SACRED HEART · Jun 3, 2024
Trial Information
Current as of July 24, 2025
Completed
Keywords
ClinConnect Summary
Lichen planus (LP) is a chronic mucocutaneous inflammatory disease of unknown etiology.
In its oral variant, oral lichen planus (OLP) has a reported prevalence ranging from 0.5% to 2.2% in the general population. The disease typically occurs between the ages of 30 and 60. Although the pathogenetic mechanism and the triggering factor remain unknown, an immune-mediated pathogenesis has been hypothesized and the role of some factors such as stress, anxiety, diabetes, other autoimmune diseases, hypertension, intestinal diseases, chronic liver diseases, hypercholesterolemia, infections, contact...
Gender
ALL
Eligibility criteria
- Inclusion Criteria (Study Group):
- • 1. Patients of both sexes, consecutively enrolled in a 1:2 ratio
- • 2. Age over 18 yo
- • 3. Previous clinical and histological diagnosis of OLP
- Exclusion Criteria (Study Group):
- • 1. Age under 18 yo
- Inclusion Criteria (Control Group):
- • 1. Patients of both sexes, consecutively enrolled in a 1:2 ratio
- • 2. Age over 18 yo
- Exclusion Criteria (Control Group):
- • 1. Age under 18 yo
- • 2. Previous clinical and histological diagnosis of OLP
About Catholic University Of The Sacred Heart
The Catholic University of the Sacred Heart is a prestigious academic institution in Italy, renowned for its commitment to advancing medical research and education. With a strong emphasis on ethical standards and community well-being, the university actively engages in clinical trials that contribute to innovative healthcare solutions. Its multidisciplinary approach leverages expertise from various fields, fostering collaborations that enhance the quality and impact of research. The university is dedicated to improving patient outcomes through rigorous science and compassionate care, aligning with its mission to serve the greater good.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Roma, , Italy
Patients applied
Trial Officials
Romeo Patini, Univ. Res.
Study Chair
Catholic University of Sacred Heart - Rome
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported