Oral Lichen Planus and Systemical Oncological Comorbidities

Launched by CATHOLIC UNIVERSITY OF THE SACRED HEART · Jun 3, 2024

Keywords

ClinConnect Summary

Lichen planus (LP) is a chronic mucocutaneous inflammatory disease of unknown etiology.

In its oral variant, oral lichen planus (OLP) has a reported prevalence ranging from 0.5% to 2.2% in the general population. The disease typically occurs between the ages of 30 and 60. Although the pathogenetic mechanism and the triggering factor remain unknown, an immune-mediated pathogenesis has been hypothesized and the role of some factors such as stress, anxiety, diabetes, other autoimmune diseases, hypertension, intestinal diseases, chronic liver diseases, hypercholesterolemia, infections, contact...

Gender

ALL

Eligibility criteria

• Inclusion Criteria (Study Group):
• • 1. Patients of both sexes, consecutively enrolled in a 1:2 ratio
• • 2. Age over 18 yo
• • 3. Previous clinical and histological diagnosis of OLP
• Exclusion Criteria (Study Group):
• • 1. Age under 18 yo
• Inclusion Criteria (Control Group):
• • 1. Patients of both sexes, consecutively enrolled in a 1:2 ratio
• • 2. Age over 18 yo
• Exclusion Criteria (Control Group):
• • 1. Age under 18 yo
• • 2. Previous clinical and histological diagnosis of OLP