Training for Men Undergoing Androgen Deprivation Therapy.

Launched by THE SWEDISH SCHOOL OF SPORT AND HEALTH SCIENCES · Jun 3, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new training program designed for men with prostate cancer who are receiving androgen deprivation therapy (ADT). The main goal is to see if this training can help reduce some of the side effects that come with ADT, such as fatigue or muscle weakness. Researchers want to find out if the training is safe to do and how well it works compared to standard care, which means participants will either follow the new training program or just receive regular treatment.

To be eligible for this trial, participants must be men aged 18 to 92 who have been diagnosed with localized or locally advanced prostate cancer and are planning to start ADT along with radiation therapy. They should be able to commit to the study procedures and not have any serious health issues that would prevent them from exercising. Those who join the study will participate in the training program twice a week for 12 weeks and will need to visit the lab at the start and after 6 and 12 weeks for check-ups. This study is currently recruiting participants, so if you or someone you know fits the criteria, it could be a great opportunity to help improve care for men undergoing ADT.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. signed informed consent
• • 2. histologically confirmed localised or locally advanced prostate cancer
• • 3. planned radiotherapy in combination with ADT for at least six months (unfavorable intermediate risk and high-risk prostate cancer) with curative intent and with no known metastasis.
• Exclusion Criteria:
• • 1. very high risk localised prostate cancer planned for radiotherapy and ADT plus abiraterone and cortisone
• • 2. localized prostate cancer planned for radiotherapy without ADT
• • 3. on-going or previously treated with ADT or other hormonal treatments
• • 4. have any contraindications to physical testing/exercise as per the ACSM guidelines
• • 5. unable to comply with study procedures