Radiographic and Histological Assessment of Autogenous Onlay Block Versus Cortical Shell on Anterior Maxilla
Launched by CAIRO UNIVERSITY · Jun 7, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different methods for helping patients who have lost bone in the front part of their upper jaw (the maxilla) and need extra bone to support dental implants. One method involves taking a piece of bone from the back of the jaw (the retromolar area) and placing it directly onto the area that needs more bone, which is called an autogenous onlay bone block. The other method uses a thinner layer of bone, known as a cortical shell, also taken from the same area. The goal is to see which method works better for improving the bone structure in these patients.
To be eligible for the trial, participants need to be between 20 and 60 years old and have at least one missing tooth in the front part of their upper jaw. They should have some remaining bone but not enough width (less than 4 mm) to support implants. Additionally, patients should not have any serious health issues that could affect healing, such as uncontrolled diabetes or certain infections. Participants will be monitored throughout the process, and the study is currently looking for volunteers. If you or someone you know meets these criteria and is interested in improving dental health, this trial might be a good opportunity.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients in both sex with partial edentulism of the maxilla and requiring horizontal ridge augmentation
- • The ages of the patients ranged from 20 to 60 years.
- • The residual ridge width in these patients are less than 4.m
- • Sufficient bone in intra-oral donor sites are available (external oblique ridge)
- • Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.
- • The vertical level should be in a favourable esthetic appearance with normal inter-arch space
- • The minimum number of missing teeth in the anterior maxilla alveolar ridge is one single extracted teeth
- Exclusion Criteria:
- • Subjected to irradiation in the head and neck area less than 1 year before implantation.
- • Poor oral hygiene and motivation.
- • Uncontrolled diabetes.
- • Pregnant or nursing.
- • Substance abuse.
- • Psychiatric problems or unrealistic expectations.
- • Severe bruxism or clenching.
- • Immunosuppressed or immunocompromised.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, Giza, Egypt
Patients applied
Trial Officials
mohamed atef, PhD
Study Director
faculty of oral and dental medicine,cairo university
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported