Impact of Regular Consumption of Eggs and Nutrients Fortified Eggs on Eczema Condition in Singapore Individuals

Launched by NATIONAL UNIVERSITY OF SINGAPORE · Jun 10, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how eating eggs every day, particularly special nutrients-fortified eggs, can help improve eczema, a skin condition that causes itching and inflammation. The researchers believe that consuming eggs might lead to better skin health for people with eczema, and the fortified eggs may provide even more benefits. The study is currently recruiting participants aged 21 to 59 who have mild to moderate eczema and are generally healthy.

To join the study, participants need to be able to read and understand English and have a body mass index (BMI) between 18.5 and 25. They should not have any significant weight changes recently or be on certain medications, including dietary supplements that could affect the results. Participants will be asked to stop using any eczema medications during the study. Those who qualify will be closely monitored, and they can expect to provide feedback on their eczema condition throughout the trial. This study is a great opportunity for eligible individuals to explore how diet can influence skin health while contributing to valuable research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. English-literate and able to give informed consent in English
• • 2. Male and female participants, aged between 21 and 59 inclusive
• • 3. Healthy individuals with no underlying condition or on regular medication
• • 4. BMI between 18.5-25 kg/m2
• • 5. Mild to moderate severity of eczema, which will also be determined using our questionnaires during the screening visit
• Exclusion Criteria:
• • 1. Significant change in body weight (3 kg or more) in the past 3 months
• • 2. Significant exercise pattern over the past 3 months defined as high-intensity exercise of more than 3 hours per week
• • 3. Known food allergy to eggs
• • 4. Taking dietary supplements which may impact the study results
• • 5. Having gastrointestinal disorders not suitable for the study
• • 6. Current smokers
• • 7. Consumes more than 2 alcoholic drinks per day i.e. one drink is defined as either 150ml of wine, 340ml of beer/cider, or 45ml of distilled spirit
• • 8. Taking lipid-lowering and blood pressure-controlling medications for less than 3 years
• • 9. Pregnant or lactating women, or planning to conceive in the next 6 months
• • 10. Unwilling to stop the medication of eczema during the study, either topical creams or oral medications
• • 11. Hierarchical link (professional and familial ties) with the research team members
• • 12. Participating in another clinical study
• • 13. Having blindness in one eye or more, eye diseases, retinal/lens/optical nerve surgery, or other eye conditions that may impact the study results
• • 14. Low-quality macular pigment optical density results were determined during the screening visit.