Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease

Launched by BEIJING ANZHEN HOSPITAL · Jun 7, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a treatment option for patients who experience a specific kind of heart problem called ventricular tachycardia (VT). VT can cause the heart to beat very fast and can be dangerous, especially if it results in low blood pressure, which means the heart isn't pumping enough blood to the body. The trial will compare two approaches: one group will receive a quick treatment called catheter ablation, while the other group will follow standard treatment methods. The goal is to see which method works better in helping patients who are experiencing serious symptoms from VT.

To be eligible for this trial, participants must be between 18 and 80 years old and have a type of heart disease. They need to have frequent episodes of VT, which means having more than three episodes in a day, and they must be experiencing low blood pressure during these episodes. However, people with certain heart conditions or recent heart surgeries, among other criteria, won't be able to participate. If you join the trial, you’ll be closely monitored by healthcare professionals, and they will provide you with care according to the study's protocols. This trial is important because it may help improve treatment options for patients with severe heart rhythm issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged 18 to 80 years;
• • 2. Having structural heart disease, including ischemic cardiomyopathy and nonischemic cardiomyopathy;
• • 3. Haemodynamically not-tolerated, defined as persistent hypotension (systolic blood pressure \<90 mmHg and mean arterial pressure 30 mmHg lower than baseline or \<70 mmHg, with associated signs of end-organ hypoperfusion);
• • 4. Electrical storm, defined as \>3 VT episodes within 24 hours.
• Exclusion Criteria:
• • 1. Reversible causes of ventricular tachycardia or cardiomyopathy;
• • 2. Ventricular thrombosis diagnosed by echocardiography and/or cardiac magnetic resonance;
• • 3. Acute ST-segment-elevation myocardial infarction within 60 days;
• • 4. Cardiac surgery within 60 days;
• • 5. Unstable angina;
• • 6. Pregnancy.