Mobile Applet for Weight Management in Obese Heart Failure Patients

Launched by HEART HEALTH RESEARCH CENTER · Jun 6, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at whether using a mobile app for diet management and an advanced weight scale can help obese patients with heart failure. The goal is to see if these tools can lower the risk of serious health issues related to heart failure, such as hospital stays and overall death rates, while also improving patients' quality of life and health status.

To participate in the trial, you need to be at least 18 years old, have certain heart function levels, and be classified as overweight or obese. If eligible, you will use the diet app during meals and weigh yourself daily for a year, along with visiting the clinic for checkups. It's important to note that the trial is not yet recruiting participants, so if you or someone you know is interested, keep an eye out for when it starts!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥18 years;
• • 2. Left ventricular ejection fraction (LVEF) ≤ 50%, with New York Heart Association (NYHA) class II-III;
• • 3. Body mass index (BMI) ≥ 26 kg/m² or male waist-to-hip ratio (WHR=waist circumference/hip circumference) ≥ 0.9, female waist-to-hip ratio ≥ 0.85;
• • 4. Ability to use a smartphone and demonstrate compliance via a diet management mobile application during a 2-week ±1-week run-in period;
• • 5. History of heart failure hospitalization within the past 6 months;
• • 6. Signed informed consent.
• Exclusion Criteria:
• • 1. End-stage heart failure (≥2 hospitalizations for heart failure in the past 3 months, intolerance to guideline-directed medical therapy (GDMT), or dependence on inotropic agents);
• • 2. Heart failure with reversible causes (e.g., peripartum cardiomyopathy, fulminant myocarditis);
• • 3. Moderate or severe anemia (hemoglobin \[Hb\] \<90 g/L);
• • 4. Renal insufficiency (estimated glomerular filtration rate \[eGFR\] \<30 mL/min/1.73 m²) or ongoing dialysis;
• • 5. Uncontrolled thyroid disease (hyperthyroidism/hypothyroidism) or end-stage liver failure;
• • 6. Alcohol or substance abuse;
• • 7. Current use of weight-loss medications or planned bariatric surgery;
• • 8. Malignancy with an expected survival \<1 year;
• • 9. Conditions potentially hindering protocol compliance, as judged by the investigator (e.g., habitual reliance on food delivery services or company cafeteria meals);
• • 10. Planned hospitalization during the trial period;
• • 11. Concurrent participation in another interventional clinical study.