Epidemiological Insights Into the Formation, Progression, and Rupture of Intracranial Aneurysms: A Retrospective, Multi-Center Hospital-Based Study in China

Launched by ZHUJIANG HOSPITAL · Jun 7, 2024

Keywords

ClinConnect Summary

This clinical trial is looking into the causes and risks associated with intracranial aneurysms, which are weak spots in the blood vessels in the brain that can lead to serious problems if they rupture. Researchers want to understand more about how these aneurysms form, progress, and what might lead to them bursting. The study is being conducted at multiple hospitals in China and is currently recruiting participants.

To be eligible to join this study, you must be at least 18 years old and have been diagnosed with an intracranial aneurysm, whether it has burst or not. It’s also important that you have complete medical records. Unfortunately, individuals under 18 or over 80, those who are pregnant, or those with certain medical conditions related to blood vessels in the brain cannot participate. If you decide to take part, you will help researchers gather important information that could lead to better understanding and treatment options for people with aneurysms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. IA diagnosis (ruptured or unruptured) or exclusion by digital subtractive angiography (DSA) or by cranial computed tomography angiography (CTA) / magnetic resonance angiography (MRA);
• • 2. Aged ≥ 18 and ≤ 18 years old;
• • 3. With complete demographic data including age and sex;
• • 4. With medical record archiving officially.
• Exclusion Criteria:
• • 1. Missing data of age, sex or hypertensive status;
• • 2. Age \<18 or \>80 years;
• • 3. Pregnancy;
• • 4. With a history of intracranial arteriovenous malformation, Moyamoya, polycystic kidney disease, Ehlers-Danlos syndrome, Gronblad-Strandberg syndrome, or Marfan syndrome;
• • 5. Suspicion for dissecting or mycotic aneurysms or aneurysm-like lesions that were indistinguishable from the infundibulum, fenestration, dilation, or atherosclerotic remodeling on structural imaging scans.