''Comparative Evaluation of Change in Bite Force and Levels of Bone Turnover Markers CTX and BALP in Hyperdivergent and Hypodivergent Cases During Retention Phases-A Prospective Clinical Trial ''
Launched by POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK · Jun 8, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating how bite force and bone health change in patients after they finish orthodontic treatment, particularly focusing on two groups: those with a hyperdivergent jaw (more horizontal growth) and those with a hypodivergent jaw (more vertical growth). The study will measure bite force and levels of specific bone markers over a 12-month period to understand how well the mouth maintains its position after treatment and how the bones are responding.
To join the study, participants must be between 18 and 25 years old, have completed their orthodontic treatment with good results, and meet certain dental health criteria. Participants can expect to wear a retainer and provide information about their dental health over the course of the year. This trial is important because it will help researchers learn more about how the mouth stabilizes after braces and how bone health is affected during this time.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Non - growing (18-25) patients who had finished Fixed orthodontic cases ( ready for debonding )with FMA of 26 or more for hyperdivergent cases and FMA of 24 or less for hypodivergent cases
- • Optimal functional occlusion at end of treatment (PAR score \>70%).
- • Littles irregularity index (Pre-treatment \<6mm in both upper and lower arch).
- • Nonsurgical and non-orthopedic patients and non syndromic patients.
- • Optimal periodontal condition and Good oral hygiene (probing depth \<3mm, gingival index score \<1
- • Good compliance regarding retainer wear
- Exclusion Criteria:
- • Subjects with incomplete orthodontic treatment.
- • TMJ disorder patients.
- • Any systemic disease affecting bone and general growth.
- • Patients with incomplete records.
- • Patient who fail to follow up or undergo complete treatment.
- • Patient with learning difficulties
- • Patients having antibiotic therapy within previous 3 months and used anti -inflammatory drugs in the month before the study
About Postgraduate Institute Of Dental Sciences Rohtak
The Postgraduate Institute of Dental Sciences, Rohtak, is a premier academic institution dedicated to advancing dental education, research, and clinical practice. With a commitment to fostering innovation in oral health, the institute is actively engaged in conducting clinical trials that aim to enhance treatment methodologies and improve patient outcomes. By integrating cutting-edge research with comprehensive training, the institute plays a pivotal role in shaping the future of dental sciences, while adhering to the highest ethical standards and regulatory guidelines in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rohtak, Haryana, India
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported