Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial

Launched by SUEZ CANAL UNIVERSITY · Jun 8, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how effective local corticosteroids (a type of medication that helps reduce inflammation and pain) and keeping a specific area of the tooth open (known as maintaining apical patency) are in lowering pain after root canal treatment for patients with a painful condition called symptomatic irreversible pulpitis in their molar teeth. The main goal is to see if using these methods can help patients feel less pain after their treatment.

To participate, you should be an adult with a painful molar tooth that has been diagnosed with irreversible pulpitis, and you should generally be healthy without any major medical issues. If you join the study, you will fill out a simple form to rate your pain after receiving treatment, which may involve using corticosteroids and maintaining apical patency. This research will help doctors understand better ways to manage pain for patients undergoing similar dental procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Symptomatic acute irreversible pulpitis in molar teeth.
• • Normal periapical condition including periapical radiography with minimal widening of periodontal ligament.
• • Normal probing depth.
• • No medical condition.
• • No contraindication for administration of corticosteroids and local anesthesia.
• Exclusion Criteria:
• • Facial or oral paresthesia.
• • Pregnancy \& breastfeeding.
• • Unrestorable tooth.
• • Marginal periodontal disease.
• • Presence of a crown on the tooth involved.
• • Over instrumentation during root canal treatment.
• • Long-term use of corticosteroids.
• • False-positive cases of sensibility test with necrosis discovered after gaining access to the tooth.
• • Cases requiring intrapulpal injection to promote anesthesia.